* Biology Meets Programming: Bioinformatics for Beginners ** Week 1 *** DNA replication **** Origin of replication (ori) Locating an ori is key for gene therapy (e.g. viral vectors), to introduce a theraupetic gene. **** Exercise: computational approach to find ori in bacteria We'll look for the *DnaA box* sequence, using a sliding window, in that case our code would be the following: #+begin_src python count = 0 
for i in range(len(Text)-len(Pattern)+1): if Text[i:i+len(Pattern)] == Pattern: count = count+1 print(Pattern + ": " + count) #+end_src *** Vocabulary - k-mer: subsquences of length /k/ in a biological sequence